This page lists fictional people in literature, film, television, and comic books who have committed or ordered mass murder, defined as the killing of four or more people in a single incident.
For fictional characters who have committed multiple separate murders over a period of time, see Category:Fictional serial killers. Note that someone who has killed in war or battle or self defense is not necessarily a murderer.
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- William "B.J." Blazkowicz
- Gaius Baltar
- Darth Bane
- Baraka (Mortal Kombat)
- Cutler Beckett
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- M. Bison
- Black Arms
- Black Hand (comics)
- Black Lantern Corps
- Black Manta
- Black Moon Clan
- Ernst Stavro Blofeld
- User blog:Sclera1/Brainiac-latest
- Eddie Brock
- Broly
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- Bryan Fury
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- Carnage (comics)
- John Cavil
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- Chaos (Sonic the Hedgehog)
- Cheshire (comics)
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- Claude Speed
- Clover (creature)
- Cobra Commander
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- Crime Syndicate of America
- Blog:Cult of Skaro
- Cult of Skaro
- User blog:Sclera1/Cult of Skaro (latest version)
- Cylon (Battlestar Galactica)
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- Scar (Fullmetal Alchemist)
- User blog:Sclera1/Brainiac
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- User blog:Sclera1/Cobra Commander
- User blog:Sclera1/Nemesis (Resident Evil)
- Scorpion (Mortal Kombat)
- Sentinel Prime
- Sephiroth (Final Fantasy)
- Shadow Galactica
- Shang Tsung
- Shao Kahn
- Shinnok
- SHODAN
- Shredder (Teenage Mutant Ninja Turtles)
- Siegfried and Nightmare
- Raoul Silva
- Sinestro
- Skeets
- Skeksis
- Agent Smith
- Supreme Leader Snoke
- Jacen Solo
- Illidan Stormrage
- Hugo Strange
- Superboy-Prime
- Sylvanas Windrunner
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